The Dawe Lab is currently comprised of two postdoctoral fellows (Jonathan and Natalie), two graduate students (David and Na), and one undergraduate (Brooke). Click above to learn more about our individual research interests.
Corn is widely used to study and illustrate mendelian traits. In corn, purple kernels are dominant over yellow kernels, and full kernels are dominant over shrunken kernels. There are four grain phenotypes in the above ear of genetic corn: Purple & Smooth, Purple & Shrunken, Yellow & Smooth and Yellow & Shrunken.
A diploid organism with 10 large chromosome pairs, corn is easily studied with the microscope. Its genetic features, including many known and mapped phenotypic mutants and a large number of progeny per cross (typically 100-200) facilitate the study of genetics and cell biology.
Immunofluorescence images from barley root tips (Han Zhang). Plant kinetochores appear to initiate their own kinetochore fibers early in prometaphase, either by directly nucleating microtubules or promoting microtubule growth in their vicinity. Chromosomes are shown in blue, spindles (tubulin) in red and kinetochore (CENH3) in green.
Meotic drive describes a variety of phenomena that “beat Mendel’s rules” and cause the preferential segregation of alleles or haplotypes to the next generation. These ears are testcrosses showing how abnormal chromosome 10 (linked to yellow kernel color) is transmitted to progeny at higher frequencies than expected ratio of 1 :1.