The Dawe LabThe Dawe Lab



D. M. Higgins, N. J. Nannas, R. K. Dawe (2016). The maize Divergent spindle-1 (dv1) gene encodes a kinesin-14A motor protein required for meiotic spindle pole organization. Frontiers in Plant Science. 7: 1277.

T. Wolfgruber, M. Nakashima, K. Schneider, A. Sharma, Z. Xie, P. Albert, R. Xu, P. Bilinski, R. K. Dawe, J. Ross-Ibarra, J. Birchler, G. Presting (2016). High quality maize centromere 10 sequence reveals evidence of frequent recombination events. Frontiers in Plant Science. 7: 308.

H. Zhao, X. Zhu, K. Wang, J. Gent, W. Zhang, R. K. Dawe, J. Jiang (2016). Gene Expression and Chromatin Modifications Associated with Maize Centromeres. G3: Genes|Genomes|Genetics 6(1): 183-192.


N. Ellis, R. Douglas, C. Jackson, J. Birchler, R. K. Dawe (2015). Generation of a Maize B Centromere Minimal Map Containing the Central Core Domain. G3: Genes|Genomes|Genetics 5(12): 2857-2864.

Q. Li, J. I Gent, G. Zynda, J. Song, I. Makarevitch, C. Hirsch, C. Hirsch, R. K. Dawe, T. Madzima, K. McGinnis, D. Lisch, R. Schmitz, M. Vaughn, N. Springer (2015). RNA-directed DNA methylation enforces boundaries between heterochromatin and euchromatin in the maize genome. PNAS 112(47): 14728-14733.

J. Gent, K. Wang, J. Jiang, R. K. Dawe (2015). Stable patterns of CENH3 occupancy through maize lineages containing genetically similar centromeres. Genetics 200(4): 1105-1116.

N. Nannas, R. K. Dawe (2015). Genetic and Genomic Toolbox of Zea mays. Genetics 199(3): 655-669.

P. Bilinski, K. Distor, J. Gutierrez-Lopez, G. Mendoza, J. Shi, R.K. Dawe, and J. Ross-Ibarra (2015). Diversity and evolution of centromere repeates in the maize genome. Chromosoma 124: 57.


J. Gent, T. Madzima, R. Bader, M. Kent, X. Zhang, M. Stam, K. McGinnis and R. K. Dawe (2014). Accessible DNA and Relative Depletion of H3K9me2 at Maize Loci Undergoing RNA-Directed DNA Methylation. Plant Cell 26(12): 4903-4917.

K. Wang, Y. Wu, W. Zhang, R.K. Dawe and J. Jiang (2014). Maize centromeres expand and adopt a uniform size in the genetic background of oat. Genome Research 24(1): 107-116.



L.B. Kanizay, P.S. Albert, J.A. Birchler and R.K. Dawe (2013). Intragenomic Conflict Between the Two Major Knob Repeats of Maize. Genetics 194(1): 81-89.


L.B. Kanizay, T. Pyhäjärvi, E.G. Lowry, M.B. Hufford, D.G. Peterson, J. Ross-Ibarra and R.K. Dawe (2013). Diversity and abundance of the Abnormal chromosome 10 meiotic drive complex in Zea mays. Heredity 110: 570-577.


Gent, J.I., N.I. Ellis, L. Guo, A.E. Harkess, Y. Yao, X. Zhang and R.K. Dawe (2013). CHH islands: de novo DNA methylation in near-gene chromatin regulation in maize. Genome Res. 23: 628-637




Ghaffari, R., E.K. Cannon, L.B. Kanizay, C.J. Lawrence and R.K. Dawe (2012). Maize chromosomal knobs are located in gene-dense areas and suppress local recombination. Chromosoma 122(1-2): 67-75.


Eichten, S.R., N.A. Ellis, I. Makarevitch, C.T. Yeh, J.I. Gent, L. Guo, K.M. McGinnis, X. Zhang, P.S. Schnable, M.W. Vaughn, R.K. Dawe and N.M. Springer (2012). Spreading of heterochromatin is limited to specific families of maize retrotransposons. PLoS Genet 8(12): e1003127.


Burgos-Rivera, B. and R.K. Dawe (2012). An Arabidopsis tissue-specific RNAi method for studying genes essential to mitosis. PLoS One 7(12): e51388.


Zhang, H., B.H. Phan, K. Wang, B.J. Artelt, J. Jiang, W.A. Parrott and R.K. Dawe (2012). Stable integration of an engineered megabase repeat array into the maize genome. Plant J 70(2): 357-365.


Zhang, H. and R.K. Dawe (2012). Total centromere size and genome size are strongly correlated in ten grass species. Chromosome Res 20(4): 403-412.


Gent, J.I., Y. Dong, J. Jiang and R.K. Dawe (2012). Strong epigenetic similarity between maize centromeric and pericentromeric regions at the level of small RNAs, DNA methylation and H3 chromatin modifications. Nucleic Acids Res 40(4): 1550-1560.


Gent, J.I. and R.K. Dawe (2012). RNA as a Structural and Regulatory Component of the Centromere. Annu Rev Genet 46: 443-453.


Fang, Z., T. Pyhajarvi, A.L. Weber, R.K. Dawe, J.C. Glaubitz, J. Gonzalez Jde, C. Ross-Ibarra, J. Doebley, P.L. Morrell and J. Ross-Ibarra (2012). Megabase-scale inversion polymorphism in the wild ancestor of maize. Genetics 191(3): 883-894.


Li, X., Topp, C.N., and R.K. Dawe (2012). Maize Antibody Procedures: Immunlocalization and Chromatin Immunoprecipitation. Plant Cytogenetics. 271-286.


M.J. Sheehan, R.K. Dawe and W.P. Pawlowski (2012). Live Imaging of Chromosome Dynamics. Plant Meiosis. 79-92.



Zhang, H. and R.K. Dawe (2011). Mechanisms of plant spindle formation. Chromosome Res 19(3): 335-344.


Gent, J.I., K.L. Schneider, C.N. Topp, C. Rodriguez, G.G. Presting and R.K. Dawe (2011). Distinct influences of tandem repeats and retrotransposons on CENH3 nucleosome positioning. Epigenetics Chromatin 4: 3.




Shi, J., S.E. Wolf, J.M. Burke, G.G. Presting, J. Ross-Ibarra and R.K. Dawe (2010). Widespread gene conversion in centromere cores. PLoS Biol 8(3): e1000327. (and associated commentary article by Talbert and Henikoff and Nature Highlight)


Du, Y., C.N. Topp and R.K. Dawe (2010). DNA binding of Centromere Protein C (CENPC) is stabilized by single stranded RNA. PLoS Genet 6(2): e1000835.




Wolfgruber, T.K., A. Sharma, K.L. Schneider, P.S. Albert, D.H. Koo, J. Shi, Z. Gao, F. Han, H. Lee, R. Xu, J. Allison, J.A. Birchler, J. Jiang, R.K. Dawe and G.G. Presting (2009). Maize centromere structure and evolution: sequence analysis of centromeres 2 and 5 reveals dynamic Loci shaped primarily by retrotransposons. PLoS Genet 5(11): e1000743.


Topp, C.N., R.J. Okagaki, J.R. Melo, R.G. Kynast, R.L. Phillips and R.K. Dawe (2009). Identification of a maize neocentromere in an oat-maize addition line. Cytogenet Genome Res 124(3-4): 228-238.


Schnable, P.S., … 155 other authors including R.K. Dawe … R.K. Wilson (2009). The B73 maize genome: complexity, diversity and dynamics. Science 326(5956): 1112-1115.


Li, X. and R.K. Dawe (2009). Fused sister kinetochores initiate the reductional division in meiosis I. Nat Cell Biol 11(9): 1103-1108.


Kanizay, L. and R.K. Dawe (2009). Centromeres: long intergenic spaces with adaptive features. Funct Integr Genomics 9(3): 287-292.


Dawe, R.K. (2009). Maize Centromeres and Knobs (neocentromeres). Handbook of Maize Genetics and Genomics. J. L. Bennetzen and S. Hake. New York, Springer. II: 239-250.




Houben, A., R.K. Dawe, J. Jiang and I. Schubert (2008). Engineered plant minichromosomes: a bottom-up success? Plant Cell 20(1): 8-10.




Phan, B.H., W. Jin, C.N. Topp, C.X. Zhong, J. Jiang, R.K. Dawe and W.A. Parrott (2007). Transformation of rice with long DNA-segments consisting of random genomic DNA or centromere-specific DNA. Transgenic Res 16(3): 341-351.


Du, Y. and R.K. Dawe (2007). Maize NDC80 is a constitutive feature of the central kinetochore. Chromosome Res 15(6): 767-775.




Topp, C.N. and R.K. Dawe (2006). Reinterpreting pericentromeric heterochromatin. Curr Opin Plant Biol 9(6): 647-653.


Shi, J. and R.K. Dawe (2006). Partitioning of the maize epigenome by the number of methyl groups on histone H3 lysines 9 and 27. Genetics 173(3): 1571-1583.


Mroczek, R.J., J.R. Melo, A.C. Luce, E.N. Hiatt and R.K. Dawe (2006). The maize Ab10 meiotic drive system maps to supernumerary sequences in a large complex haplotype. Genetics 174(1): 145-154.


Luce, A.C., A. Sharma, O.S. Mollere, T.K. Wolfgruber, K. Nagaki, J. Jiang, G.G. Presting and R.K. Dawe (2006). Precise centromere mapping using a combination of repeat junction markers and chromatin immunoprecipitation-polymerase chain reaction. . Genetics 174(2): 1057-1061.


Dawe, R.K. and S. Henikoff (2006). Centromeres put epigenetics in the driver’s seat. Trends Biochem Sci 31(12): 662-669.




Zhang, X., X. Li, J.B. Marshall, C.X. Zhong and R.K. Dawe (2005). Phosphoserines on maize CENTROMERIC HISTONE H3 and histone H3 demarcate the centromere and pericentromere during chromosome segregation. Plant Cell 17(2): 572-583.


Jin, W., J.C. Lamb, J.M. Vega, R.K. Dawe, J.A. Birchler and J. Jiang (2005). Molecular and functional dissection of the maize B chromosome centromere. Plant Cell 17(5): 1412-1423.


Dawe, R.K., E.A. Richardson and X. Zhang (2005). The simple ultrastructure of the maize kinetochore fits a two-domain model. Cytogenet Genome Res 109(1-3): 128-133.


Dawe, R.K. (2005). . Centromere renewal and replacement in the plant kingdom. Proc Natl Acad Sci U S A 102(33): 11573-11574.




Topp, C.N., C.X. Zhong and R.K. Dawe (2004). Centromere-encoded RNAs are integral components of the maize kinetochore. Proc Natl Acad Sci U S A 101(45): 15986-15991.


Lawrence, C.J., C.M. Zmasek, R.K. Dawe and R.L. Malmberg (2004). LumberJack: a heuristic tool for sequence alignment exploration and phylogenetic inference. Bioinformatics 20(12): 1977-1979.


Lawrence, C.J., R.K. Dawe, K.R. Christie, D.W. Cleveland, S.C. Dawson, S.A. Endow, L.S. Goldstein, H.V. Goodson, N. Hirokawa, J. Howard, R.L. Malmberg, J.R. McIntosh, H. Miki, T.J. Mitchison, Y. Okada, A.S. Reddy, W.M. Saxton, M. Schliwa, J.M. Scholey, R.D. Vale, C.E. Walczak and L. Wordeman (2004). A standardized kinesin nomenclature. J Cell Biol 167(1): 19-22.


Jin, W., J.R. Melo, K. Nagaki, P.B. Talbert, S. Henikoff, R.K. Dawe and J. Jiang (2004). Maize centromeres: organization and functional adaptation in the genetic background of oat. Plant Cell 16(3): 571-581.


Dawe, R.K. and E.N. Hiatt (2004). Plant neocentromeres: fast, focused, and driven. Chromosome Res 12(6): 655-669.


Dawe, R.K. (2004). RNA interference on chromosomes. Nat Genet 36(11): 1141-1142.




Nagaki, K., P.B. Talbert, C.X. Zhong, R.K. Dawe, S. Henikoff and J. Jiang (2003). Chromatin immunoprecipitation reveals that the 180-bp satellite repeat is the key functional DNA element of Arabidopsis thaliana centromeres. Genetics 163(3): 1221-1225.


Nagaki, K., J. Song, R.M. Stupar, A.S. Parokonny, Q. Yuan, S. Ouyang, J. Liu, J. Hsiao, K.M. Jones, R.K. Dawe, C.R. Buell and J. Jiang (2003). Molecular and cytological analyses of large tracks of centromeric DNA reveal the structure and evolutionary dynamics of maize centromeres. Genetics 163(2): 759-770.


Mroczek, R.J. and R.K. Dawe (2003). Distribution of retroelements in centromeres and neocentromeres of maize. Genetics 165(2): 809-819.


Jiang, J., J.A. Birchler, W.A. Parrott and R.K. Dawe (2003). A molecular view of plant centromeres. Trends Plant Sci 8(12): 570-575.


Hiatt, E.N. and R.K. Dawe (2003). The meiotic drive system on maize abnormal chromosome 10 contains few essential genes. Genetica 117(1): 67-76.


Hiatt, E.N. and R.K. Dawe (2003). Four loci on abnormal chromosome 10 contribute to meiotic drive in maize. Genetics 164(2): 699-709.


Dawe, R.K. (2003). RNA interference, transposons, and the centromere. Plant Cell 15(2): 297-301.


Birchler, J.A., R.K. Dawe and J.F. Doebley (2003). Marcus Rhoades, preferential segregation and meiotic drive. Genetics 164(3): 835-841.




Zhong, C.X., J.B. Marshall, C. Topp, R. Mroczek, A. Kato, K. Nagaki, J.A. Birchler, J. Jiang and R.K. Dawe (2002). Centromeric retroelements and satellites interact with maize kinetochore protein CENH3. Plant Cell 14(11): 2825-2836.


Lawrence, C.J., R.L. Malmberg, M.G. Muszynski and R.K. Dawe (2002). Maximum likelihood methods reveal conservation of function among closely related kinesin families. J Mol Evol 54(1): 42-53.


Hiatt, E.N., E.K. Kentner and R.K. Dawe (2002). Independently regulated neocentromere activity of two classes of tandem repeat arrays. Plant Cell 14(2): 407-420.


2001 & earlier


Lawrence, C.J., N.R. Morris, R.B. Meagher and R.K. Dawe (2001). Dyneins have run their course in plant lineage. Traffic 2(5): 362-363.


Yu, H.G., E.N. Hiatt and R.K. Dawe (2000). The plant kinetochore. Trends Plant Sci 5(12): 543-547.


Yu, H.G. and R.K. Dawe (2000). Functional redundancy in the maize meiotic kinetochore. J Cell Biol 151(1): 131-142.


Yu, H.G., M.G. Muszynski and R. Kelly Dawe (1999). The maize homologue of the cell cycle checkpoint protein MAD2 reveals kinetochore substructure and contrasting mitotic and meiotic localization patterns. J Cell Biol 145(3): 425-435.


Dawe, R.K., L.M. Reed, H.G. Yu, M.G. Muszynski and E.N. Hiatt (1999). A maize homolog of mammalian CENPC is a constitutive component of the inner kinetochore. Plant Cell 11(7): 1227-1238.


Buckler, E.S.t., T.L. Phelps-Durr, C.S. Buckler, R.K. Dawe, J.F. Doebley and T.P. Holtsford (1999). Meiotic drive of chromosomal knobs reshaped the maize genome. Genetics 153(1): 415-426.


Richards, E.J. and R.K. Dawe (1998). Plant centromeres: structure and control. Curr Opin Plant Biol 1(2): 130-135.


Dawe, R.K. (1998). Meiotic chromosome organization and segregation in plants. Annual Review of Plant Physiology and Plant Molecular Biology 49: 371-395.


Yu, H.G., E.N. Hiatt, A. Chan, M. Sweeney and R.K. Dawe (1997). Neocentromere-mediated chromosome movement in maize. J Cell Biol 139(4): 831-840.


Starr, D.A., B.C. Williams, Z. Li, B. Etemad-Moghadam, R.K. Dawe and M.L. Goldberg (1997). Conservation of the centromere/kinetochore protein ZW10. J Cell Biol 138(6): 1289-1301.


Dawe, R.K. and W.Z. Cande (1996). Induction of centromeric activity in maize by suppressor of meiotic drive 1. Proc Natl Acad Sci U S A 93(16): 8512-8517.


Dawe, R.K., J.W. Sedat, D.A. Agard and W.Z. Cande (1994). Meiotic chromosome pairing in maize is associated with a novel chromatin organization. Cell 76(5): 901-912.