The Dawe LabThe Dawe Lab

Our Research

CENPC localization reveals kinetochore dynamics: Neocentromeres extend towards the spindle poles. CENPC staining is red, tubulin is blue and DNA is green. The signmal appears yellow when red (CENPC) and green (DNA) overlap.

We study how chromosomes segregate in plants. We wonder how the centromeres organize the overlying kinetochores and how the kinetochores ensure accurate chromosome segregation. We want to know what plant centromeres are made of, how they are inherited, what proteins interact with them, and how they evolve. What are centromeres? For over fifteen years our lab has been working through the answers to these questions. By clicking through the links below and throughout our website, you can find more details on our work and the people who work here.

 

Kinetochores

Centromeres

Neocentromeres

Heterochromatin